ALIYAH 1 - REBECCA'S TWINS.
Isaac and Rebecca are childless, and pray for children. After 20 years of marriage, Rebecca conceives, and gives birth to twins. The first-born, hairy and ruddy, they name Esau; the second, born grasping his brother's heel, they name Jacob [ Ya'aqov | יַֽעֲקֹ֑ב ]. Esau is an outdoorsman, and Isaac favors him, while Rebecca is partial to the more indoorsy Jacob.
Esau, returning hungry from a hunt, prevails upon Jacob to give him some of the stew that Jacob is cooking - in return for which, Jacob extracts Esau's promised birthright.
A famine strikes the land of Canaan, but G-d instructs Isaac not to travel to Egypt as his father Abraham did, but to remain in the land.
ALIYAH 2 - ISAAC AND AVIMELEKH.
Isaac presents his wife Rebecca to the local people as his "sister", the third instance of such a ruse in Genesis. After time passes, he lets his guard down and is spotted behaving intimately with Rebecca. Avimelekh chastises him, and Isaac reaps "a hundredfold" as a blessing from G-d.
ALIYAH 3 - ISAAC DOES WELL.
Isaac prospers, and is asked by Avimelekh to leave the area. He resettles, first in Gerar (along the border between the Negev and the Israeli heartland, and just east of Gaza), then at Sitnah; after encountering trouble over wells with the locals at these locations, he finally settles in Rehovoth [רְחוֹבוֹת] in the Negev. (This is not the same as the modern city of the same name, which is about 20 km south of Tel Aviv.)
ALIYAH 4
Isaac travels to Be'er Sheva, where he receives a nighttime visit from G-d with the promise of safety and of many descendants. He is then visited by Avimelekh, who proposes improved relations and a pact of peace. [292]